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Decapeptide-12

CAT: 0931-T75714-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T75714-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
137665-91-9
Target
Tyrosinase|||Sirtuin
Related Pathways
Proteases/Proteasome|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
Decapeptide-12, a competitive inhibitor of mushroom tyrosinase with an IC50 of 40 µM and a Kd of 61.1 ?M for the C-terminal residue of tyrosinase, is a small oligopeptide that reduces melanin content in melanocytes by interacting with tyrosinase and increasing transcription of SIRT. It is utilized in researching melanogenesis, senescence, and inflammation [1] [2] [3].
Smiles
C([C@@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)CO)=O)CO)=O)C=4C=5C(NC4)=CC=CC5
Molecular Formula
KS3WY3
Molecular Weight
1395.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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