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MM-401 TFA

CAT: 0931-T75258-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T75258-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1442106-11-7
Target
Others, Histone Methyltransferase, Apoptosis
Related Pathways
Apoptosis, Others, Chromatin/Epigenetic
Bioactivity
MM-401 (TFA), an MLL1 H3K4 methyltransferase inhibitor, effectively impedes MLL1 activity (IC 50 = 0.32 μM) by preventing MLL1-WDR5 interaction. It can induce cell cycle arrest, apoptosis, and differentiation, offering potential for MLL leukemia research [1].
Smiles
C(C(O)=O)(F)(F)F.O=C1[C@H](NC(=O)[C@H](CC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@](NC(C(C)C)=O)(C)CCCCN1)C2=CC=CC=C2
Molecular Formula
C31H47F3N8O7
Molecular Weight
700.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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