MM-401 TFA

• CAS Number :

  1442106-11-7

• Target :

  Others|||Histone Methyltransferase|||Apoptosis

• Related Pathways :

  Apoptosis|||Others|||Chromatin/Epigenetic

• Bioactivity :

  MM-401 (TFA), an MLL1 H3K4 methyltransferase inhibitor, effectively impedes MLL1 activity (IC 50 = 0.32 µM) by preventing MLL1-WDR5 interaction. It can induce cell cycle arrest, apoptosis, and differentiation, offering potential for MLL leukemia research [1].

• Smiles :

  C(C(O)=O)(F)(F)F.O=C1[C@H](NC(=O)[C@H](CC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@](NC(C(C)C)=O)(C)CCCCN1)C2=CC=CC=C2

• Molecular Formula :

  C31H47F3N8O7

• Molecular Weight :

  700.75

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C