Peptide 401

CAT: 0931-TP1408-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-TP1408-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

32908-73-9

Target

Histamine Receptor, 5-HT Receptor

Related Pathways

Immunology/Inflammation, Neuroscience, GPCR/G Protein

Bioactivity

Peptide 401 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps. Peptide 401 induces mast cell degranulation, activating histamine release from peritoneal mast cells. Additionally, peptide 401 exhibits some anti-inflammatory activity, decreasing paw edema in animal models.

Smiles

O=C1[C@]2(N(C(=O)[C@H](CCCCN)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@]4(NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCCN)=O)CSSC[C@](NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CC5=CN=CN5)N1)[H])(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CCCCN)=O)=O)CSSC4)[H])[H])[H])[H])CCC2)[H]

Molecular Formula

C110H192N40O24S4

Molecular Weight

2587.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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