MM-102 TFA

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9978

• Bioactivity:

  MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor with an IC50 of 2.4 nM. This compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5), inhibiting MLL1 H3K4 histone methyltransferase (HMT) activity and down-regulating H3K4me3, which facilitates the epigenetic reprogramming of porcine somatic cell nuclear transfer embryos.

• Smiles:

  OC (=O) C (F) (F) F.CCC (CC) (NC (=O) C (C) C) C (=O) N[C@@H] (CCCNC (N) =N) C (=O) NC1 (CCCC1) C (=O) NC (c1ccc (F) cc1) c1ccc (F) cc1

• Molecular Formula:

  C37H50F5N7O6

• Molecular Weight:

  783.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1883545-52-5