GBR-401

• Target :

  Immunology/Inflammation related

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for Fc?RIIIa. It exhibits potent cytotoxicity in vitro and in vivo against various B-cell malignancies. GBR-401 induces cell death through antibody-dependent cellular cytotoxicity (ADCC) and direct cytotoxic effects. In severe combined immunodeficiency (SCID) mouse models with various xenografts, GBR-401 effectively eliminates malignant B cells and prolongs survival.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1931954-95-8