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HER2-IN-13

CAT: 0931-T75164-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T75164-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414056-34-9
Target
Potassium Channel, EGFR, Others
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Membrane transporter/Ion channel, Others
Bioactivity
HER2-IN-13 (Compound 33) is an effective HER2 inhibitor with an IC50 value of 8 nM and also inhibits wt-EGFR with an IC50 of 0.40 μM [1].
Smiles
O(C=1C=2C(NC3=CC(Cl)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@H]6C(F)(F)CN(C)CC6
Molecular Formula
C26H23ClF2N8O3
Molecular Weight
568.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C