HER2-IN-19

• Target:

  EGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis

• Bioactivity:

  HER2-IN-19 (Compound 10e) is a potent inhibitor of HER2 and EGFR, with IC50 values of 0.87 and 3.5 nM, respectively. It shows significant inhibitory activity against tumor cells, with IC50 values for NCI-N87, BT474, and BaF3-HER2YVMA being 1.63 nM, 15.17 nM, and 1.49 nM, respectively.

• Molecular Formula:

  C30H29ClN6O2

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C