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Anticancer agent 114

CAT: 0931-T74839-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T74839-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Proteasome
Related Pathways
Ubiquitination|||Others|||Proteases/Proteasome
Bioactivity
Anticancer agent 114, a dipeptide boronic acid ester, functions as a potent proteasome inhibitor with an oral activity and demonstrates an IC50 of 2.2 nM. It exhibits antiproliferative properties specifically targeting RPMI-8226 cells, making it valuable for research into multiple myeloma [1].
Molecular Formula
C28H33BF6N2O7
Molecular Weight
634.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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