Chol-CTPP

• Target:

  Others|||Apoptosis|||Reactive Oxygen Species

• Related Pathways:

  Metabolism|||Immunology/Inflammation|||Others|||NF-?B|||Apoptosis

• Bioactivity:

  Chol-CTPP, a ligand with a dual targeting effect on the blood-brain barrier (BBB) and glioma cells, serves as the precursor to Lip-CTPP when combined with another mitochondria-targeting ligand (Chol-TPP) . Lip-CTPP emerges as a potential carrier facilitating the collaborative anti-glioma efficacy of doxorubicin (DOX) and lonidamine (LND) . It significantly enhances the inhibition of tumor cell proliferation, migration, and invasion, promotes apoptosis and necrosis, and disrupts mitochondrial function [1].

• Molecular Formula:

  C144H263N3O53

• Molecular Weight:

  2884.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C