Chol-CTPP

• Target :

  Others|||Apoptosis|||Reactive Oxygen Species

• Related Pathways :

  Metabolism|||Immunology/Inflammation|||Others|||NF-?B|||Apoptosis

• Bioactivity :

  Chol-CTPP, a ligand with a dual targeting effect on the blood-brain barrier (BBB) and glioma cells, serves as the precursor to Lip-CTPP when combined with another mitochondria-targeting ligand (Chol-TPP) . Lip-CTPP emerges as a potential carrier facilitating the collaborative anti-glioma efficacy of doxorubicin (DOX) and lonidamine (LND) . It significantly enhances the inhibition of tumor cell proliferation, migration, and invasion, promotes apoptosis and necrosis, and disrupts mitochondrial function [1].

• Molecular Formula :

  C144H263N3O53

• Molecular Weight :

  2884.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C