IZ-Chol

IZ-Chol

• CAS Number: 191990-35-9
• UNSPSC Description: IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect[1].
• Target Antigen: Liposome
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/iz-chol.html
• Smiles: C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCN4C=CN=C4)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C
• Molecular Weight: 537.82
• References & Citations: [1]Yajing Wang, et al. Design, synthesis, and in vitro gene transfer efficacy of novel ionizable cholesterol derivatives. J Liposome Res. 2024 Apr 2:1-13.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported