IZ-Chol

CAT: 0804-HY-159859Size: 5 mg (46.48 mM x 200 μL in Ethanol)Dry Ice: NoHazardous: No

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CAT#:0804-HY-159859Size:5 mg (46.48 mM x 200 μL in Ethanol)

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect[1].

CAS Number

191990-35-9

UNSPSC

12352005

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/iz-chol.html

Concentration

46.48 mM * 200 μL in Ethanol

Purity

99.37

Smiles

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCN4C=CN=C4)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C

Molecular Formula

C34H55N3O2

Molecular Weight

537.82

References & Citations

[1]Yajing Wang, et al. Design, synthesis, and in vitro gene transfer efficacy of novel ionizable cholesterol derivatives. J Liposome Res. 2024 Apr 2:1-13.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

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Catalog	Name
HY-N16312	Chol-mPEG3400
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HY-144825	Chol-CTPP
HY-136869-01	MHAPC-Chol
HY-W590538	HAPC-Chol
HY-N15843	Chol-mPEG2000
HY-152901-01	Chol-N3
HY-125529-01	DMPAC-Chol
HY-125734	DMHAPC-Chol
HY-145523-01	OH-Chol

Alternative Products

Catalog	Name
574259	MHAPC-Chol
MBS5798405	DMPAC-Chol
MBS5816329	Chol-CTPP
GTR19191168-01	DMHAPC-Chol
TYD-04091-01	Chol-mPEG3400
MBS5824379	Chol-N3
T74363-01	Chol-TPP
MBS5798015	OH-Chol
MBS5816284	Chol-PEG
T37035-01	HAPC-Chol

IZ-Chol

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