IZ-Chol

• Description :

  IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect[1].

• UNSPSC :

  12352005

• Target :

  Liposome

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/iz-chol.html

• Concentration :

  46.48 mM * 200 μL in Ethanol

• Purity :

  99.37

• Smiles :

  C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCN4C=CN=C4)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C

• Molecular Formula :

  C34H55N3O2

• Molecular Weight :

  537.82

• References & Citations :

  [1]Yajing Wang, et al. Design, synthesis, and in vitro gene transfer efficacy of novel ionizable cholesterol derivatives. J Liposome Res. 2024 Apr 2:1-13.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported

• CAS Number :

  [191990-35-9]