DMPAC-Chol

CAT: 0931-T37534-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T37534-01Size:1 mg
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CAS Number
184582-91-0
Target
Liposome|||Others
Related Pathways
Others|||Metabolism
Bioactivity
DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 ?g/ml.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C[C@@H](OC(NCCCN(C)C)=O)CC2)[H])[H]
Molecular Formula
C33H58N2O2
Molecular Weight
514.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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