DMPAC-Chol

• Target:

  Liposome|||Others

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 ?g/ml.

• Smiles:

  C[C@@]12[C@@]3 ([C@] ([C@]4 ([C@] (C) (CC3) [C@@] ([C@@H] (CCCC (C) C) C) (CC4) [H]) [H]) (CC=C1C[C@@H] (OC (NCCCN (C) C) =O) CC2) [H]) [H]

• Molecular Formula:

  C33H58N2O2

• Molecular Weight:

  514.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  184582-91-0