OH-Chol

• Target :

  Others|||Liposome

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  OH-Chol is a cationic cholesterol derivative. OH-Chol, as a component of lipoplexes with [DOPE], has been used for siRNA delivery and gene silencing in MCF-7 cells and in mice via intravenous injection, resulting in lipoplex accumulation in the liver. Additionally, it has been employed in cationic nanoparticles with [Tween 80] to transfect pDNA and siRNA into PC3 mouse xenografts via intratumoral injection and with [Tween 80] and [folate-PEG2000-DSPE] in a KB mouse xenograft model for intratumoral gene delivery.

• Smiles :

  [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)NCCNCCO)[C@H](C)CCCC(C)C|t:9|

• Molecular Formula :

  C32H56N2O2

• Molecular Weight :

  500.812

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  191173-82-7