HL-8

• Target :

  PI3K|||Others

• Related Pathways :

  PI3K/Akt/mTOR signaling|||Others

• Bioactivity :

  HL-8, a PROTAC molecule, effectively targets and degrades PI3K kinase completely at a concentration of 10 ?M within 8 hours, showcasing potential for cancer research [1].

• Smiles :

  COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncc(-c3nnc(o3)-c3ccccc3C(=O)NCCCCCCC(=O)N[C@H](C(=O)N3C[C@@H](O)C[C@@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)n2c1

• Molecular Formula :

  C57H59F2N11O9S2

• Molecular Weight :

  1144.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2766352-64-9