HL-PEG2k

• UNSPSC Description:

  HL-PEG2k is a second near-infrared Ru(II) polypyridyl complex. HL-PEG2k exhibits a wavelength bathochromic shift, enhanced photothermal conversion efficiency (41.77%), and an antineoplastic effect against glioma. HL-PEG2k displays a superior biocompatibility and thus can be a potential theranostic platform to combat the growth and recurrence of tumors[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hl-peg2k.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[PEG2000]OC)CCC(C=C1)=CC=C1N(C2=CC=CC=C2)C(C=C3)=CC=C3C4=C(N=S=N5)C5=C(C(C=C6)=CC=C6N(C7=CC=C(CCC(N[PEG2000]OC)=O)C=C7)C8=CC=CC=C8)C9=NC%10=C(C=CC=[N]%11[Ru]%12%13([N]%14=CC=CC=C%14C%15=[N]%12C=CC=C%15)([N]%16=C(C%17=CC=CC=[N]%17%13)C=CC=C%16)[N]%18=CC=C%19)C%11=C%18C%19=C%10N=C94.[2+].[2Cl-]

• References & Citations:

  [1]Liu Y, et al. A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy. J Med Chem. 2022;65(3):2225-2237.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported