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ADH-6

CAT: 0931-T73533-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73533-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2227429-65-2
Target
Others, MDM-2/p53, Apoptosis
Related Pathways
Others, Apoptosis
Bioactivity
ADH-6, a tripyridylamide compound, impedes the self-assembly of the aggregation-nucleating subdomain of mutant p53 DNA-binding domain (DBD) . By targeting and dissociating mutant p53 aggregates in human cancer cells, ADH-6 reinstates p53's transcriptional activity, culminating in cell cycle arrest and apoptosis, thereby holding potential for cancer research.
Smiles
N(C(=O)C=1N=C(OCCCC)C(N(=O)=O)=CC1)C2=C(OCCCN)N=C(C(NC3=C(OCCCN)N=C(C(OC)=O)C=C3)=O)C=C2
Molecular Formula
C29H36N8O9
Molecular Weight
640.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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