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ADH-1 trifluoroacetate

CAT: 0931-T1608-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T1608-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1135237-88-5
Target
Cadherin
Related Pathways
Cytoskeletal Signaling
Purity
0.9998
Bioactivity
ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis.
Smiles
OC(=O)C(F)(F)F.CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(N)=O)NC(C)=O
Molecular Formula
C24H35F3N8O8S2
Molecular Weight
684.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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MBS3845847-01ADH-1 trifluoroacetate
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A21417-2ADH-1 trifluoroacetate 2mg
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A21417-100ADH-1 trifluoroacetate 100mg
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