Products for Research Use Only
RegisterLogin

(Rac) -PF-184

CAT: 0804-HY-107591Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107591Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(Rac) -PF-184 is a potent inhibitory factor-κB kinase 2 (IKK-2) inhibitor with an IC50 of 37 nM. (Rac) -PF-184 has anti-inflammatory effects[1].
CAS Number
1187460-81-6
UNSPSC
12352005
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rac-pf-184.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C2=C1CCC3=C2C=C(NC(C4=CC(N5CC(CO)(C(CO)(C5)C)C)=NC=C4Cl)=O)C=C3)C6=CC=C(C=C6)F)N
Molecular Formula
C32H32ClFN6O4
Molecular Weight
619.09
References & Citations
[1]Sommers CD, et al. Novel tight-binding inhibitory factor-kappaB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation. J Pharmacol Exp Ther. 2009 Aug;330 (2) :377-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IKK-β

Related Products

CatalogName
HY-107591BPF-184
HY-119943A-01(Rac) -PF-06256142
HY-13245B-01(Rac) -PF-4136309
HY-117900A(Rac) -PF-06250112
HY-14250A-01(Rac) -PF-998425
HY-106016HP 184
HY-155482-01NA-184
HY-15249-01JZL 184
HY-P1172TCS 184
HY-14220CB-184

Alternative Products

CatalogName
GTR19204980-01(Rac) -PF-06250112
GTR19189884(Rac) -PF-998425
MBS5802674(Rac)-PF-998425
JPC58097-01(Rac) -PF-06256142
T61281-01(Rac)-PF-06256142
MBS5767461(Rac)-PF-06250112
A11136-10(Rac) -PF-4136309 ((Rac) -INCB8761) 10mg
A11136-5(Rac) -PF-4136309 ((Rac) -INCB8761) 5mg
A11136-100(Rac) -PF-4136309 ((Rac) -INCB8761) 100mg
A11136-50(Rac) -PF-4136309 ((Rac) -INCB8761) 50mg

Popular Products