CB-184

CAT: 0931-T201560-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T201560-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

165307-47-1

Target

Apoptosis, Sigma receptor

Related Pathways

GPCR/G Protein, Apoptosis

Bioactivity

CB-184 is a selective ligand for sigma-2 (σ2) receptors, with Ki values of 7436 nM for sigma-1 (σ1) and 13.4 nM for sigma-2 (σ2), and it promotes apoptosis with antitumor activity.

Smiles

O=C\1C[C@@]2(C[C@](/C1=C\C3=CC(Cl)=C(Cl)C=C3)(N(C)CC2)[H])C4=CC(O)=CC=C4

Molecular Formula

C22H21Cl2NO2

Molecular Weight

402.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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