Products for Research Use Only

EDP-305

CAT: 0931-T73414-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73414-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1933507-63-1
Target
FXR, Phosphatase, Cytochromes P450, Others
Related Pathways
Others, Metabolism
Bioactivity
EDP-305, an orally active, potent, and selective agonist of the farnesoid X receptor (FXR), exhibits EC50 values of 34 nM in chimeric FXR within CHO cells and 8 nM in full-length FXR in HEK cells. Demonstrating a potent and consistent antifibrotic effect, EDP-305 is utilized in research related to primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH) .
Smiles
O[C@H]1[C@@]2([C@@]([C@]3(C)[C@]([C@H]1CC)(C[C@H](O)CC3)[H])(CC[C@@]4(C)[C@]2(CC[C@@]4([C@@H](CCNC(NS(=O)(=O)C5=CC=C(C(C)(C)C)C=C5)=O)C)[H])[H])[H])[H]
Molecular Formula
C36H58N2O5S
Molecular Weight
630.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C