ACT-777991

• Target:

  Others|||CXCR

• Related Pathways:

  Immunology/Inflammation|||Autophagy|||GPCR/G Protein|||Others

• Bioactivity:

  ACT-777991 is an orally active, selective CXCR3 antagonist with demonstrated stability in microsomes and hepatocytes across various animal models. This compound effectively inhibits the migration of activated T cells toward CXCL11.

• Smiles:

  C (F) (F) (F) C=1SC (=C (N1) C=2C=NC (C (F) (F) F) =NC2) N3C[C@@H] (CCO) N (C (CN4N=C (C) N=C4) =O) CC3

• Molecular Formula:

  C20H20F6N8O2S

• Molecular Weight:

  550.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1967811-46-6