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ACT-777991

CAT: 0931-T73148-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73148-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1967811-46-6
Target
Others, CXCR
Related Pathways
Immunology/Inflammation, Autophagy, GPCR/G Protein, Others
Bioactivity
ACT-777991 is an orally active, selective CXCR3 antagonist with demonstrated stability in microsomes and hepatocytes across various animal models. This compound effectively inhibits the migration of activated T cells toward CXCL11.
Smiles
C(F)(F)(F)C=1SC(=C(N1)C=2C=NC(C(F)(F)F)=NC2)N3C[C@@H](CCO)N(C(CN4N=C(C)N=C4)=O)CC3
Molecular Formula
C20H20F6N8O2S
Molecular Weight
550.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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