ACT-660602

• Target:

  Others|||CXCR

• Related Pathways:

  Others|||Autophagy|||GPCR/G Protein|||Immunology/Inflammation

• Bioactivity:

  ACT-660602 is an orally active chemokine receptor CXCR3 antagonist (IC50: 204 nM) that inhibits T cell migration and has demonstrated significant efficacy in an in vivo model of acute lung injury. It is useful for studying autoimmune diseases.

• Smiles:

  C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F

• Molecular Formula:

  C20H20F6N8OS

• Molecular Weight:

  534.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1646267-59-5