BAY 1214784

• Target:

  Others|||GNRH Receptor

• Related Pathways:

  GPCR/G Protein|||Others

• Purity:

  1

• Bioactivity:

  BAY 1214784, a potent, selective, and orally active spiroindoline derivative compound, serves as an antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R) . It notably reduces plasma luteinizing hormone levels by up to 49%, demonstrating low pharmacokinetic variability and good tolerability. This compound shows promise for research into uterine fibroids.

• Smiles:

  S (=O) (=O) (N1[C@@H] (C2 (C=3C1=CC=C (C (NCC4=C (Cl) C=C (C (F) (F) F) C=N4) =O) C3) CCS (=O) (=O) CC2) [C@@H]5CC5) C6=CC=C (F) C=C6

• Molecular Formula:

  C29H26ClF4N3O5S2

• Molecular Weight:

  672.11

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1631164-25-4