BAY-390

• Target:

  Others|||TRP/TRPV Channel

• Related Pathways:

  Others|||Membrane transporter/Ion channel

• Bioactivity:

  BAY-390 is a brain-penetrating, species-agnostic inhibitor of TRPA1, exhibiting selective inhibition of human and rat TRPA1 with IC50 values of 16 nM for hTRPA1 FLIPR, 82 nM for hTRPA1 Ephys, 63 nM for rTRPA1 FLIPR, and 35 nM for rDRG Ephys. It holds potential for inflammation research applications.

• Smiles:

  N([C@H]1[C@]([C@](F)(F)F)(O)CCCC1)C2=CC=C(F)C=C2

• Molecular Formula:

  C13H15F4NO

• Molecular Weight:

  277.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2741956-55-6