BAY-707

• Target :

  DNA/RNA Synthesis|||Others

• Related Pathways :

  Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity :

  BAY-707, a highly potent and selective substrate-competitive inhibitor of MTH1 (NUDT1) with an IC50 of 2.3 nM, is well-tolerated in mice and exhibits a favorable pharmacokinetic (PK) profile compared to other MTH1 compounds. However, it demonstrates a clear lack of anticancer efficacy both in vitro and in vivo[1].

• Smiles :

  C(NCC)(=O)C1=CC2=C(C=CN=C2N1)N3[C@@H](C)COCC3

• Molecular Formula :

  C15H20N4O2

• Molecular Weight :

  288.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2109805-96-9