BAY-707

CAT: 0931-T14509-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T14509-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2109805-96-9
Target
DNA/RNA Synthesis|||Others
Related Pathways
Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
BAY-707, a highly potent and selective substrate-competitive inhibitor of MTH1 (NUDT1) with an IC50 of 2.3 nM, is well-tolerated in mice and exhibits a favorable pharmacokinetic (PK) profile compared to other MTH1 compounds. However, it demonstrates a clear lack of anticancer efficacy both in vitro and in vivo[1].
Smiles
C(NCC)(=O)C1=CC2=C(C=CN=C2N1)N3[C@@H](C)COCC3
Molecular Formula
C15H20N4O2
Molecular Weight
288.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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