G4/HDAC-IN-1

CAT: 0931-T72946-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T72946-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

DNA/RNA Synthesis, Others, HDAC

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Chromatin/Epigenetic

Bioactivity

G4/HDAC-IN-1, a dual-targeting compound for G4 and HDAC, shows inhibition of intracellular HDAC activity, with an IC50 value of 1.1 μM, and promotes G4 formation. It effectively inhibits proliferation and tumor growth in a TNBC xenograft model, presenting potential for cancer research applications.

Smiles

CN(C)CCCNC(=O)C1=CC=C(C=C1)/C=C/2\CCN3C2=NC4=CC(=C(C=C4C3=O)F)N5CCN(CC5)CCCCCCCC(=O)NO.Cl

Molecular Formula

C36H49ClFN7O4

Molecular Weight

698.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-132914	CDK/HDAC-IN-1
HY-141844	HDAC/BET-IN-1
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G4/HDAC-IN-1

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