(Rac) -Lonafarnib

• Target :

  Others|||Transferase

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  (Rac) -Lonafarnib (Sch66336 racemate) is the racemic form of the potent, orally active farnesyl transferase (FTase) inhibitor, Lonafarnib. It effectively inhibits H-ras, K-ras, and N-ras with IC50 values of 1.9 nM, 5.2 nM, and 2.8 nM, respectively, and exhibits activities against the hepatitis delta virus (HDV) .

• Smiles :

  BrC1=C2C(C=3C(CCC2=CC(Cl)=C1)=CC(Br)=CN3)C4CCN(C(CC5CCN(C(N)=O)CC5)=O)CC4

• Molecular Formula :

  C27H31Br2ClN4O2

• Molecular Weight :

  638.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  193275-86-4