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Rac-Belinostat

CAT: 0931-T1852-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T1852-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
414864-00-9
Target
Autophagy, HDAC
Related Pathways
Autophagy, Chromatin/Epigenetic, DNA Damage/DNA Repair
Purity
0.9996
Bioactivity
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
Smiles
ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1
Molecular Formula
C15H14N2O4S
Molecular Weight
318.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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