Lonafarnib

• Target:

  Autophagy|||Ras|||Raf|||Kras|||Transferase

• Related Pathways:

  MAPK|||Autophagy|||Metabolism|||GPCR/G Protein

• Purity:

  0.9994

• Bioactivity:

  Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM) .

• Smiles:

  NC (=O) N1CCC (CC (=O) N2CCC (CC2) [C@H]2c3ncc (Br) cc3CCc3cc (Cl) cc (Br) c23) CC1

• Molecular Formula:

  C27H31Br2ClN4O2

• Molecular Weight:

  638.82

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  193275-84-2