Products for Research Use Only

Anticancer agent 59

CAT: 0931-T72476-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72476-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, ROS Kinase, Apoptosis
Related Pathways
Others, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
Anticancer agent 59, an inhibitor active against various cancer cell lines, particularly demonstrates efficacy in A549 cells with an IC 50 value of 0.2 μM. It prompts apoptosis, elevates Ca2+ and ROS levels within cancer cells, and markedly reduces mitochondrial membrane potential. Additionally, it effectively curtails tumor growth in the A549 mouse xenograft model.
Smiles
CCC(=O)O[C@H]1CC[C@]2(C(C1(C)C)CC[C@@]3(C2C(=O)C=C4[C@]3(CC[C@@]5([C@H]4C[C@@](CC5)(C)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)O)C)C)C)C
Molecular Formula
C42H59NO6
Molecular Weight
673.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C