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LC kinetic stabilizer-1

CAT: 0931-T72285-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72285-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2495750-19-9
Target
Others
Related Pathways
Others
Bioactivity
LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WIL-FL represents an amyloidogenic FL LC dimer.
Smiles
CC=1C=2C(=CC(N(CC)CC)=CC2)OC(=O)C1CCNC(NCC3=CC(=CC=C3)C4=CN=CN4)=O
Molecular Formula
C27H31N5O3
Molecular Weight
473.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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