LC kinetic stabilizer-1

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WIL-FL represents an amyloidogenic FL LC dimer.

• Smiles:

  CC=1C=2C(=CC(N(CC)CC)=CC2)OC(=O)C1CCNC(NCC3=CC(=CC=C3)C4=CN=CN4)=O

• Molecular Formula:

  C27H31N5O3

• Molecular Weight:

  473.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2495750-19-9