Products for Research Use Only

LC-1-40

CAT: 0931-T209447-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209447-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, Apoptosis, DNA/RNA Synthesis
Related Pathways
Apoptosis, PROTAC, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM) . In mouse models, LC-1-40 selectively inhibits tumor growth induced by MYCN and induces nucleotide damage and apoptosis (cell death) in MYCN-associated tumors. It is applicable for cancer research.
Molecular Formula
C49H48N8O6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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