LC-1-40

• Target:

  PROTACs|||Apoptosis|||DNA/RNA Synthesis

• Related Pathways:

  Apoptosis|||PROTAC|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Bioactivity:

  LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM) . In mouse models, LC-1-40 selectively inhibits tumor growth induced by MYCN and induces nucleotide damage and apoptosis (cell death) in MYCN-associated tumors. It is applicable for cancer research.

• Molecular Formula:

  C49H48N8O6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C