RK-20448

• Target:

  VEGFR|||Tie-2|||Others|||Src

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Others|||Angiogenesis

• Bioactivity:

  RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2. It also inhibits BLK, Csk, Fyn, and Lyn. RK-20448 is the cis isomer of A-419259

• Smiles:

  NC1=C2C (=CN (C2=NC=N1) [C@@H]3CC[C@@H] (CC3) N4CCN (C) CC4) C5=CC=C (OC6=CC=CC=C6) C=C5

• Molecular Formula:

  C29H34N6O

• Molecular Weight:

  482.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  479501-40-1