AM-9514

CAT: 0931-T70639-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T70639-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1442677-18-0
Target
Others
Related Pathways
Others
Bioactivity
AM-9514 is a novel, potent Glucokinase (GK) activator. AM-9514 showed a favorable combination of in vitro potency, enzyme kinetic properties, acceptable pharmacokinetic profiles in preclinical species, and robust efficacy in a rodent PD model. Glucokinase (GK) activators represent a class of type 2 diabetes therapeutics actively pursued due to the central role that GK plays in regulating glucose homeostasis.
Smiles
O(C1=C(NC(NC)=O)N=CC([C@@H](O)[C@]2(C[C@](C)(O)C2)[H])=C1)C=3N(CC)N=CC3
Molecular Formula
C18H25N5O4
Molecular Weight
375.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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