TTC-352

• CAS Number :

  1607819-68-0

• Target :

  Estrogen Receptor/ERR|||Others

• Related Pathways :

  Others|||Endocrinology/Hormones

• Bioactivity :

  TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells.

• Smiles :

  O(C1=C(C=2C(S1)=CC(O)=CC2)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4

• Molecular Formula :

  C20H13FO3S

• Molecular Weight :

  352.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C