BTM-3528

• Target :

  PERK|||Mitochondrial Metabolism|||Apoptosis

• Related Pathways :

  Apoptosis|||Metabolism

• Purity :

  0.9937

• Bioactivity :

  BTM-3528 is an activator of the mitochondrial protease OMA1 with anticancer activity.BTM-3528 activates the ISR via the mitochondrial protease OMA1, inducing OMA1-dependent cleavage of DELE1 and OPA1 and mitochondrial fragmentation.BTM-3528 induces cell growth arrest and apoptosis.

• Smiles :

  O=C(O)C1=C(C=2C=CC=C(F)C2)C(=NN1C3=NC(=C(S3)SC(C)C)C=4C=CC(=CC4)C(F)(F)F)C

• Molecular Formula :

  C24H19F4N3O2S2

• Molecular Weight :

  521.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2054998-45-5