4A-MPLA (ammonium)

• Description:

  4A-MPLA (ammonium) can be used as an adjuvant in vaccine. 4A-MPLA (ammonium) induces tissue-specific immune response. 4A-MPLA (ammonium) can enhance resistance against endotoxin induced effects in host and decrease cytokine production during infection[1][2].

• UNSPSC:

  12352005

• Target:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Smiles:

  O[C@@H]([C@@H]([C@H]([C@H](O1)O)NC(C[C@@H](CCCCCCCCCCC)O)=O)OC(C[C@H](O)CCCCCCCCCCC)=O)[C@H]1CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(O)(O)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCC)=O)=O.N

• Molecular Formula:

  C68H132N3O19P

• Molecular Weight:

  1326.76

• References & Citations:

  [1]Watts, B. A., et al., (2019) . Monophosphoryl lipid A induces protection against LPS in medullary thick ascending limb through induction of Tollip and negative regulation of IRAK-1. American journal of physiology. Renal physiology, 317 (3), F705–F719.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [2260669-09-6]