Products for Research Use Only
RegisterLogin

SR1903 TFA

CAT: 0931-T69671-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T69671-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2351884-03-0
Target
Others
Related Pathways
Others
Bioactivity
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR) . It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated receptor γ (PPAR) but does not activate it. SR-1903 inhibits LPS-induced expression of triggering receptor expressed on myeloid cells 1 (TREM-1) . It also inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1. SR-1903 reduces the severity of collagen-induced arthritis. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity.
Smiles
C(C(O)=O)(F)(F)F.CC1=C(C2=CC=C(C(C(F)(F)F)(C(F)(F)F)O)C=C2)C=CC(CN3CCN(CC=4C=CN=CC4)CC3)=C1
Molecular Formula
C29H28F9N3O3
Molecular Weight
637.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T83742-01SBP1 TFA
T83736-01RTDLDSLRTYTL TFA
T83714-01LAP TFA
T83707-01F9170 TFA
T83702-01E70K TFA
T75801-01TC14012 TFA
T33876L1-01Panomifene TFA
T68166L-01Traxanox TFA
T36201L-01AZD5582 TFA
T33836L-01Oxamisole TFA

Alternative Products

CatalogName
MBS5812219SR1903 TFA
574023SR1903 free base
NBP3-22491-50ulRabbit Monoclonal NPY5R Antibody (SR1903)

Popular Products