CCW 28-3

• Target :

  Others|||PROTACs|||Epigenetic Reader Domain

• Related Pathways :

  PROTAC|||Others|||Chromatin/Epigenetic

• Bioactivity :

  CCW 28-3 is a novel potent covalent BRD4 degrader, degrading BRD4 in a proteasome- and RNF4-dependent manner without inhibiting RNF4 autoubiquitination activity.

• Smiles :

  CC=1C2=C(N3C([C@H](CC(NCCCCOC4=CC=C(OC5=CC=C(N(CC6=CC=CC=C6)C(CCl)=O)C=C5)C=C4)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C

• Molecular Formula :

  C44H42Cl2N6O4S

• Molecular Weight :

  821.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2361142-23-4