PX-478

• Target:

  HIF|||Autophagy|||HIF/HIF Prolyl-Hydroxylase

• Related Pathways:

  Angiogenesis|||Autophagy|||Chromatin/Epigenetic|||Metabolism

• Purity:

  0.9979

• Bioactivity:

  PX-478 is a HIF-1? inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic ?-cell function in diabetes mellitus and is used in type 2 diabetes mellitus research.

• Smiles:

  Cl.Cl.N[C@@H](Cc1ccc(cc1)[N+]([O-])(CCCl)CCCl)C(O)=O

• Molecular Formula:

  C13H20Cl4N2O3

• Molecular Weight:

  394.12

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  685898-44-6