YM-202074

CAT: 0931-MF-0144114-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0144114-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
299900-83-7
Target
Others|||GluR
Related Pathways
Others|||Neuroscience
Bioactivity
YM-202074 is a high affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM-202074 binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. It inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells) .
Smiles
C(N(C)C1CCCCC1)(=O)C2=CN3C=4C(N=C3S2)=CC=C(CN(CCOC)C)C4
Molecular Formula
C22H30N4O2S
Molecular Weight
414.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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