YM-341619

• Target:

  Others|||STAT

• Related Pathways:

  Others|||JAK/STAT signaling|||Stem Cells

• Bioactivity:

  YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM) that inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, without affecting Th1 cell differentiation. YM-341619 holds potential for research into allergic diseases, such as allergic asthma.

• Smiles:

  NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)ccc(F)c1F

• Molecular Formula:

  C22H21F3N6O2

• Molecular Weight:

  458.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  643082-52-4