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Antiproliferative agent-72

CAT: 0931-T212526-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212526-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1052646-54-4
Target
HSP
Related Pathways
Metabolism, Cytoskeletal Signaling
Bioactivity
Antiproliferative agent-72 (Compound 10) is an Hsp90 inhibitor with a dissociation constant (Kd) of 11 nM. It exhibits antiproliferative activity with IC50 values of 1.5 μM and 1.1 μM against HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 is suitable for cancer research applications.
Smiles
ClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(=NC2=C4)N)=C3
Molecular Formula
C20H17Cl2N3O2S
Molecular Weight
434.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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