DNMT2-IN-2

• Target:

  DNA Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  DNMT2-IN-2 is a selective inhibitor of DNA methyltransferase 2 (DNMT2) with a KD value of 3.04 ?M. It targets a concealed allosteric binding site of DNMT2 and reduces m5C levels in tRNA of MOLM-13 cells. This compound works synergistically with Doxorubicin to impair cell viability and is applicable in cancer research, including studies of cervical cancer and leukemia.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C