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DNMT2-IN-2

CAT: 0013-GTR19264561-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264561-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNMT2-IN-2 is a selective inhibitor of DNA methyltransferase 2 (DNMT2) with a KD value of 3.04 μM. It targets a concealed allosteric binding site of DNMT2 and reduces m5C levels in tRNA of MOLM-13 cells. This compound works synergistically with Doxorubicin to impair cell viability and is applicable in cancer research, including studies of cervical cancer and leukemia.
Field of Research
Epigenetics & Chromatin, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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