Factor B-IN-6

• Target:

  Complement System

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  Factor B-IN-6 is an orally bioavailable inhibitor of Factor B. It exhibits significant inhibitory activity on the activation of the human serum alternative pathway. In model animals, Factor B-IN-6 can improve kidney lesions and function, reducing urinary protein levels. Factor B-IN-6 is applicable for kidney disease research.

• Smiles:

  C(C1=C2C(=C(C)C=C1OC)NC=C2)N3[C@@H](C[C@H](CC3)[C@H]4CC(F)(F)C4)C5=CC=C(C(O)=O)C=C5

• Molecular Formula:

  C27H30F2N2O3

• Molecular Weight:

  468.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2797066-55-6