Factor B-IN-1

CAT:

931-T38969

Size:

5 mg

Price:

Ask

CAS Number :
1481631-75-7
Target :
Others|||Complement System
Related Pathways :
Immunology/Inflammation|||Others
Bioactivity :
Factor B-IN-1 is a Factor B inhibitor (IC50 = 43 nM) and is an analog of compound 13. It is used to inhibit complement pathway factor B and has improved pharmacokinetic properties (oral availability in rats and dogs) .
Smiles :
COc1cc(C)c2[nH]ccc2c1C(O)c1nc2ccc(cc2[nH]1)C#N
Molecular Formula :
C19H16N4O2
Molecular Weight :
332.3559
Shipping Conditions :
Cool pack
Storage Temperature :
-20°C

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144743	IL-4 (B Cell IgG differentiation factor, B Cell growth factor 1, B Cell stimulatory factor 1)
MBS6000290-01	NFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B)
397493	NFIB (Nuclear Factor 1 B-Type, NF1-B, Nuclear Factor 1/B, CCAAT-Box-Binding Transcription Factor, CTF, Nuclear Factor I/B, NF-I/B, NFI-B, TGGCA-Binding Protein)
130333	NFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B)
130334	NFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B)
MBS6004789-01	NFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B)
477901	CHAF1B (Chromatin Assembly Factor 1 Subunit B, Chromatin Assembly Factor 1, Subunit B (p60) )
492702	SPIB (Transcription Factor Spi-B, Spi-B Transcription Factor (Spi-1/PU.1 Related) )