Factor B-IN-1

CAT: 0931-T38969Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T38969Size:5 mg
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CAS Number
1481631-75-7
Target
Others|||Complement System
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
Factor B-IN-1 is a Factor B inhibitor (IC50 = 43 nM) and is an analog of compound 13. It is used to inhibit complement pathway factor B and has improved pharmacokinetic properties (oral availability in rats and dogs) .
Smiles
COc1cc(C)c2[nH]ccc2c1C(O)c1nc2ccc(cc2[nH]1)C#N
Molecular Formula
C19H16N4O2
Molecular Weight
332.3559
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5799527Factor B-IN-1
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MBS6000290-01NFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B)
397493NFIB (Nuclear Factor 1 B-Type, NF1-B, Nuclear Factor 1/B, CCAAT-Box-Binding Transcription Factor, CTF, Nuclear Factor I/B, NF-I/B, NFI-B, TGGCA-Binding Protein)
492702SPIB (Transcription Factor Spi-B, Spi-B Transcription Factor (Spi-1/PU.1 Related) )
477901CHAF1B (Chromatin Assembly Factor 1 Subunit B, Chromatin Assembly Factor 1, Subunit B (p60) )
S5490SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related), Spi-B, Transcription Factor Spi-B) discontinued
130334-APCNFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B) (APC)
MBS6137864-01NFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B) APC
130334-BiotinNFIB (Nuclear Factor 1 B-type, CCAAT-box-binding Transcription Factor, Nuclear Factor I/B, TGGCA-binding Protein, NF1-B, Nuclear Factor 1/B, CTF, NF-I/B, NFI-B) (Biotin)

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