DH-18

• Target :

  MMP|||Apoptosis

• Related Pathways :

  Proteases/Proteasome|||Apoptosis

• Bioactivity :

  DH-18 is an inhibitor of matrix metalloproteinase-2 (MMP-2), exhibiting IC50 values of 139.45 nM for MMP-2, 518.11 nM for MMP-9, and 833.34 nM for MMP-8. The compound promotes cell apoptosis and causes cell cycle arrest in the G0/G1 phase. DH-18 also inhibits cell growth, making it potential for research in chronic myeloid leukemia.

• Molecular Formula :

  C26H23F6N3O5S

• Molecular Weight :

  603.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C