DPP8/9-IN-2

CAT: 0931-T211988-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T211988-01Size: 10 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Sodium Channel|||Potassium Channel|||Calcium Channel|||Proteasome
Related Pathways
Membrane transporter/Ion channel|||Proteases/Proteasome|||Ubiquitination|||Metabolism
Bioactivity
DPP8/9-IN-2 (Compound 21) is an inhibitor targeting DPP8 and DPP9 with IC50 values of 0.22 nM and 3 nM, and Ki values of 2.9 nM and 6 nM, respectively. It exhibits certain cardiac toxicity, with IC50 values against the hERG potassium channel, Nav1.5 sodium channel, and Cav1.2 calcium channel of 0.7 ?M, 29.0 ?M, and 27.7 ?M. DPP8/9-IN-2 is applicable for research into diseases such as cancer.
Shipping Conditions
Cool pack
Storage Temperature
-20°C