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DPP8/9-IN-2

CAT: 0931-T211988-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211988-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Sodium Channel, Potassium Channel, Calcium Channel, Proteasome
Related Pathways
Membrane transporter/Ion channel, Proteases/Proteasome, Ubiquitination, Metabolism
Bioactivity
DPP8/9-IN-2 (Compound 21) is an inhibitor targeting DPP8 and DPP9 with IC50 values of 0.22 nM and 3 nM, and Ki values of 2.9 nM and 6 nM, respectively. It exhibits certain cardiac toxicity, with IC50 values against the hERG potassium channel, Nav1.5 sodium channel, and Cav1.2 calcium channel of 0.7 μM, 29.0 μM, and 27.7 μM. DPP8/9-IN-2 is applicable for research into diseases such as cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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