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DPP8/9-IN-1

CAT: 0931-T206718-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206718-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome
Bioactivity
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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