ATF3-IN-1

CAT: 0931-T211966-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T211966-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2952703-90-9

Target

Ferroptosis, Epigenetic Reader Domain, Glutathione Peroxidase, ROS

Related Pathways

Chromatin/Epigenetic, Apoptosis, Metabolism, Immunology/Inflammation

Bioactivity

ATF3-IN-1 is an inhibitor of both ferroptosis and ATF3. It mitigates oxidative stress and ferroptosis through the ATF3/SLC7A11/GPX4 pathway, offering protection against ischemic stroke. ATF3-IN-1 can reduce ischemia/reperfusion (I/R) injury and enhance neuron survival, demonstrating neuroprotective effects, making it valuable for ischemic stroke research.

Smiles

O=C1C(OC)=C(OC)C(=O)C(=C1C)CCCCCCCCCCOC(=O)N2CCOCC2

Molecular Formula

C24H37NO7

Molecular Weight

451.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-175032-01	ATF3-IN-1
C15141-01	ATF3 inducer 1
BZ0161-2	PcDNA3.1-ATF3
pka-270	ATF3
P32289	PExpress-1-Atf3 (rat)
PVT41408	pExpress-1-Atf3 Plasmid
70R-31623	ATF3 antibody

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